Title: Costs of integrating HIV self-testing in public health facilities in Malawi, South Africa, Zambia and Zimbabwe
Authors:
Linda Alinafe Sande, Katleho Matsimela, Lawrence Mwenge, Collin Mangenah, Augustine Talumba Choko, Marc d’Elbée, Mohammed Majam, Cyprian Mostert, Inonge Matamwandi, Euphemia Lindelwe Sibanda, Cheryl Johnson, Karin Hatzold, Helen Ayles, Frances M Cowan, Elizabeth Lucy Corbett, Melissa Neuman , Hendramoorthy Maheswaran, Gesine Meyer-Rath, Fern Terris-Prestholt
ABSTRACT
Introduction As countries approach the UNAIDS 95-95-95 targets, there is a need for innovative and cost-saving HIV testing approaches that can increase testing coverage in hard-to-reach populations. The HIV Self-Testing Africa-Initiative distributed HIV selftest (HIVST) kits using unincentivised HIV testing counsellors across 31 public facilities in Malawi, South Africa, Zambia and Zimbabwe. HIVST was distributed either through secondary (partner’s use) distribution alone or primary (own use) and secondary distribution approaches.
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Title: Secondary HIV self-test distribution increases male partner testing
Authors: Sibanda EL, Mavhu W
Abstract
There is established evidence that men are less likely than women to engage with HIV services; the latest global estimates show that, compared with women, 1 million more men living with HIV do not know their status, 1·8 million know their status but are not on treatment, and 1·6 million are not virally suppressed.1
Elimination of HIV requires concerted efforts to ensure that men are not left behind. Male partners of pregnant women are particularly important to engage to optimise HIV outcomes for themselves, their pregnant or lactating partners, and their babies, because incident maternal infection during breastfeeding is the largest contributor to postpartum mother-to-child transmission of HIV…
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Title: Effect of peer-distributed HIV self-test kits on demand for biomedical HIV prevention in rural KwaZulu-Natal, South Africa: a three-armed cluster-randomised trial comparing social networks versus direct delivery
Authors:
Shahmanesh M, Mthiyane TN, Herbsst C, Neuman M, Adeagbo O, Mee P, Chimbindi N, Smit T, Okesola N, Harling G, McGrath N, Sherr L, Seeley J, Subedar H, Johnson C, Hatzold K, Terris-Prestholt F, Cowan FM, Corbett EL
Abstract:
Study objective: We investigated two peer distribution models of HIV self-testing (HIVST) in HIV prevention demand creation compared with trained young community members (peer navigators)…
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Title: Innovative demand creation strategies to increase voluntary medical male circumcision uptake: a pragmatic randomised controlled trial in Zimbabwe
Authors: Mavhu W, Neuman M, Hatzold K, Buzuzi S, Maringwa G, Chabata ST, Mangenah C, Taruberekera N, Madidi N, Munjoma M, Ncube G, Xaba S, Mugurungi O, Johnson CC, Corbett EL, Weiss HA, Fielding K, Cowan FM
Abstract:
Reaching men aged 20–35 years, the group at greatest risk of HIV, with voluntary medical male circumcision (VMMC) remains a challenge. We assessed the impact of two VMMC demand creation approaches targeting this age group in a randomised controlled trial (RCT)…
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Title: Relative efficiency of demand creation strategies to increase voluntary medical male circumcision uptake: a study conducted as part of a randomised controlled trial in Zimbabwe.
Authors
Mangenah C, Mavhu W, Garcia DC, Gavi C, Mleya P, Chiwawa P, Chidawanyika S, Ncube G, Xaba S, Mugurungi O, Taruberekera N, Madidi N, Fielding KL, Johnson C, Hatzold K, Terris-Prestholt F, Cowan FM
Abstract
Supply and demand-side factors continue to undermine voluntary medical male circumcision (VMMC) uptake. We assessed relative economic costs of four VMMC demand creation/service-delivery modalities as part of a randomised controlled trial in Zimbabwe.
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Title: Adolescent girls who sell sex in Zimbabwe: HIV risk, behaviours and service engagement. Journal of Acquired Immune Deficiency Syndromes (1999).
Authors: Rice, B., Machingura, F., Maringwa, G., Magutshwa, S., Kujeke, T., Jamali, G., Busza, J., de Wit, M., Fearon, E., Hanisch, D. and Yekeye, R., 2022.
Abstract
Background
To reduce HIV incidence among adolescent girls who sell sex (AGSS) in Zimbabwe, we need to better understand how vulnerabilities intersect with HIV infection and how those living with HIV engage in care.
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Title: Experiences and lessons learned from the real-world implementation of an HIV recent infection testing algorithm in three routine service-delivery settings in Kenya and Zimbabwe.
Authors: Mariken de Wit, Brian Rice, Kathryn Risher, Susie Welty, Wanjiru Waruiru, Sitholubuhle Magutshwa, John Motoku, Daniel Kwaro, Benard Ochieng, Georges Reniers, Frances M Cowan, George Rutherford, James Hargreaves, Gary Murphy. BMC Health Serv Res 21, 596 (2021).
Abstract
Testing for recent HIV infection can distinguish recently acquired infection from long-standing infections. Given current interest in the implementation of recent infection testing algorithms (RITA), we report our experiences in implementing a RITA in three pilot studies and highlight important issues to consider when conducting recency testing in routine settings
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Title: It went through the roof”: an observation study exploring the rise in PrEP uptake among Zimbabwean female sex workers in response to adaptations during Covid-19.
Authors:
Matambanadzo P, Busza J, Mafaune H, Chinyanganya L, Machingura F, Ncube G, Steen R, Phillips A, Cowan FM.
Abstract:
Introduction: Sisters with a Voice (Sisters), a programme providing community-led differentiated HIV prevention and treatment services, including condoms, HIV testing, pre-exposure prophylaxis (PrEP) and antiretroviral therapy linkage for sex workers, reached over 26,000 female sex workers (FSW) across Zimbabwe in 2020. Zimbabwe’s initial Covid “lockdown” in March 2020 and associated movement restrictions interrupted clinical service provision for 6 weeks, particularly in mobile clinics, triggering the adaptation of services for the Covid-19 context and a scale up of differentiated service delivery (DSD) models. PrEP service delivery decentralized with shifts from clinical settings towards community/home-based, peer-led PrEP services to expand and maintain access. We hypothesize that peer-led community-based provision of PrEP services influenced both demand and supply-side determinants of PrEP uptake. We observed the effect of these adaptations on PrEP uptake among FSW accessing services in Sisters in 2020.
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Title: Potential Reduction in Female Sex Workers’ Risk of Contracting HIV during Covid-19
Authors
Fortunate Machingura, Sungai T Chabata, Joanna Busza, Gracious Jamali, Memory Makamba, Jeffrey Dirawo, Raymond Yekeye, Owen Mugurungi, Primrose Matambanadzo, Frances Mary Cowan
Abstract
Female sex workers’ livelihoods in Zimbabwe have been severely impacted by the coronavirus disease 2019 pandemic due to closure of entertainment venues. Competition over fewer clients has reduced ability to negotiate condom use. At the same time as partner numbers have decreased, frequency of reported condomless sex has not increased, suggesting potential reduction in overall HIV and sexually transmitted infection risk and an opportunity for programmes to reach sex workers with holistic social and economic support and prevention services.
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Title: ART initiations following community-based distribution of HIV self-tests: meta-analysis and meta-regression of STAR Initiative data
Authors:
Neuman M, Fielding KL, Ayles H, Cowan FM, Hensen B, Indravudh PP, Johnson C, Sibanda EL, Hatzold K, Corbett EL.
Abstract
Measuring linkage after community-based testing, particularly HIV self-testing (HIVST), is challenging. Here, we use data from studies of community-based HIVST distribution, conducted within the STAR Initiative, to assess initiation of antiretroviral therapy (ART) and factors driving differences in linkage rates.
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Title: Efficiency in PrEP Delivery: Estimating the Annual Costs of Oral PrEP in Zimbabwe
Authors:
Mangenah C, Nhamo D, Gudukeya S, Gwavava E, Gavi C, Chiwawa P, Chidawanyika S, Muleya P, Taruberekera N, Madidi N, Ncube G, Bara H, Napierala S, Dunbar M, Hoke T, Kripke K, Cowan FM, Torjesen K, Terris-Prestholt F
Abstract
Although oral PrEP is highly effective at preventing HIV acquisition, optimizing continuation among beneficiaries is challenging in many settings. We estimated the costs of delivering oral PrEP to populations at risk of HIV in seven clinics in Zimbabwe. Full annual economic costs of oral PrEP initiations and continuation visits were estimated from the providers’ perspective for a six-clinic NGO network and one government SGBV clinic in Zimbabwe (January-December 2018)…
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Title: Comparison of community-led distribution of HIV self-tests kits with distribution by paid distributors: a cluster randomised trial in rural Zimbabwean communities
Authors:
Sibanda EL, Mangenah C, Neuman M, Tumushime M, Watadzaushe C, Mutseta MN, Maringwa G, Dirawo J, Fielding KL, Johnson C, Ncube G, Taegtmeyer M, Hatzold K, Corbett EL, Terris-Prestholt F, Cowan FM.
Abstract
We compared community-led versus an established community-based HIV self-testing (HIVST) model in rural Zimbabwe using a cluster-randomised trial.
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Title: Community-based HIV self-testing: a cluster-randomised trial of supply-side financial incentives and time-trend analysis of linkage to antiretroviral therapy in Zimbabwe.
Authors:
Sibanda EL, Neuman M, Tumushime M, Mangenah C, Hatzold K, Watadzaushe C, Mutseta MN, Dirawo J, Napierala S, Ncube G, Terris-Prestholt F, Taegtmeyer M, Johnson C, Fielding KL, Weiss HA, Corbett E, Cowan FM.
Title: Values and preferences of contraceptive methods: a mixed-methods study among sex workers from diverse settings.
Authors:
Sibanda E, Shapiro A, Mathers B, Verster A, Baggaley R, Gaffield ME, Macdonald V.
Title: Child disciplinary practices, abuse, and neglect: Findings from a formative study in Chitungwiza, Zimbabwe.
Authors:
Patel SN, Shanmugam I, Obong’o C, Mupambireyi Z, Kasese C, Bangani Z, Miller KS.
Title: Provision of HIV viral load testing services in Zimbabwe: Secondary data analyses using data from health facilities using the electronic Patient Monitoring System.
Authors:
Apollo T, Takarinda KC, Phillips A, Ndhlovu C, Cowan FM.
Title: How Can We Support the Use of Oral PrEP Among Young Women who Sell Sex? A PrEP Cascade Analysis.
Authors:
Hensen B, Machingura F, Busza J, Birdthistle I, Chabata ST, Chiyaka T, Floyd S, Jamali G, Mushati P, Hargreaves J, Cowan FM.
Title: The impact of the DREAMS partnership on HIV incidence among young women who sell sex in two Zimbabwean cities: results of a non-randomised study.
Authors:
Chabata ST, Hensen B, Chiyaka T, Mushati P, Musemburi S, Dirawo J, Busza J, Floyd S, Birdthistle I, Hargreaves JR, Cowan FM
Title: Antiretroviral therapy dispensing for patients who are clinically stable.
Authors:
Sibanda E, Taegtmeyer M.
Title: ‘I was trying to get there, but I couldn’t’: social norms, vulnerability and lived experiences of home delivery in Mashonaland Central Province, Zimbabwe.
Authors;
Webb KA, Mavhu W, Langhaug L, Chitiyo V, Matyanga P, Charashika P, Patel D, Prost A, Ferrand RA, Bernays S, Cislaghi B, Neuman M.
Title: What’s in a Name? A Mixed Method Study on How Young Women Who Sell Sex Characterize Male Partners and Their Use of Condoms.
Authors:
Busza J, Hensen B, Birdthistle I, Chabata ST, Hargreaves JR, Floyd S, Chiyaka T, Mushati P, Cowan FM. J
Title: Feasibility and acceptability of a peer-led HIV self-testing model among female sex workers in Malawi: a qualitative study.
Authors:
Kumwenda MK, Mavhu W, Lora WS, Chilongosi R, Sikwese S, Taegtmeyer M, Hatzold K, Johnson CC, Corbett EL, Desmond N.